Welcome to the Molecular and Cellular Biology research cluster in the Department of Biological Sciences at Wright State University. Our goal is to expose students to multidisciplinary training opportunities and provide broad exposure to fundamental molecular and cellular processes. Our research laboratories employ a wide range of biological systems including the nematode Caenorhabditis, gray treefrogs, dust mites, human airway epithelia, human keratinocytes, mammalian cell lines, adenovirus, human immunodeficiency virus (HIV), and herpes simplex virus (HSV). In addition, molecular evolution studies in several of these laboratories focus on organisms ranging from prokaryotes to waterfowl to humans.
Our research laboratories are training grounds for undergraduate students as well as graduate students from the Wright State Master of Science Program in Biological Sciences, the Wright State Biomedical Sciences Ph.D. Program, and the Wright State Environmental Sciences Ph.D. Program. Principal Investigators and their trainees sustain research awards from funding agencies such as the National Institutes of Health and the National Science Foundation, as well as from private companies and research foundations.
Brief descriptions of Molecular and Cellular Biology faculty research interests are listed below. For more thorough descriptions of research and training opportunities, please view the websites of individual faculty members.
- Host-parasite interactions; inflammatory and immune response to scabies mites
Larry Arlian, Ph.D.
- Speciation genetics; morphological evolution; evolution of adaptive gene complexes
Scott Baird, Ph.D.
- Structure/function of nuclear organelles; regulation of gene expression; genome integrity
Athanasios Bubulya, Ph.D.
- Adenovirus biology; virus-cell interactions; cell surface receptors; gene therapy
Kate Excoffon, Ph.D.
- Freeze tolerance in amphibians; aquaporin transport in cryobiology; kidney function
David Goldstein, Ph.D.
- Chemoreceptor sensing and neuronal response to changes in blood gases and pH
Lynn Hartzler, Ph.D.
- Cellular mechanisms for wound healing in skin; cellular mechanisms of defense against HSV-1
Barbara Hull, Ph.D.
- Molecular evolution and genetic diversity; DNA bioinformatics; forensic DNA analysis
Dan Krane, Ph.D.
- HIV Rev-microtubule interactions and cell proliferation; protein glycosylation in disease
Mill Miller, Ph.D.
- Evolution of populations/species; influence of natural selection on non-coding DNA
Jeffrey Peters, Ph.D.
- Stem cell biology and regeneration in flatworms; Regulation of gene expression; RNA
Labib Rouhana, Ph.D.
- Cytotoxicity of Lou Gehrig's disease proteins; Development of novel therapeutic approaches
Shulin Ju, Ph.D.
- Interactome networks--evolutionary rewiring and perturbations in disease
Quan Zhong, Ph.D.
- Cellular and molecular physiology of mammalian skeletal muscle and the neuromuscular junction
Andrew Voss, Ph.D.