About

Biochemistry and Molecular Biology Research

Paliy Lab

The research in Dr. Oleg Paliy’s Laboratory is focused on the studies of complex microbial communities associated with human gastrointestinal system.

Vijay Shankar continues his research in Dr. Paliy's lab after graduating with his Ph.D. in the spring. His research involves the use of high-throughput sequencing technologies and multivariate statistics to interrogate the community structure, function and metabolic capabilities of human gut microbiomes in health and disease. Shankar was also published in Molecular Ecology "Application of multivariate statistical techniques in microbial ecology” 

Ghaith Fallata compressed.jpgSecond year master’s student Ghaith Fallata is researching the interaction of gut microbes and the immune response to allergic diseases. Fallata, majoring in Microbiology and Immunology, is looking at how the gut microbiota interact with host immune reactions by studying metabolites that are formed through microbial fermentation that act as proinflammatory signals. He does this by isolating metabolites from gastrointestinal sources and determining their composition through nuclear magnetic resonance (NMR) spectroscopy.

 

Dr. John PaiettaPaietta journal published FEB2016.jpg

Associate Professor Dr. John Paietta contributed a chapter to "The Handbook of Microbial Metabolism of Amino Acids".  Chapter 15 called "Regulation of Sulfur Metabolism in Filamentous Fungi" and was published in Biochemistry and Molecular Biology in February 2016. 

 

 

Dr. Michael Leffak

Nucleic Acids Research.jpgProfessor and Vice Chair of Research Dr. Michael Leffak was published in Nucleic Acids Research in May 2016. The article is titled “FANCJ is essential to maintain micro satellite structure genome-wide during replication stress” 

He was also published in June of 2016 in Cell Research, “MutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesis”